Dogs
Potentially toxicConsulted references classify the plant as toxic or irritating for that pet type.
Verified against ASPCA/provenance audit 2026-05-06 on May 6, 2026.
dog safety reference
Is Mayapple safe for dogs?
Podophyllum peltatum
American Mandrake is a perennial woodland plant known for its umbrella-like leaves and single white flower. It contains podophyllotoxin, which is highly irritating and potentially dangerous if ingested by pets.
American MayappleMayapplePodophyllum peltatumWild Mandrake
- Light
- Part shade to full shade
- Habit
- Rhizomatous perennial
- Care
- Low
Safety status
What this means for your dog
Mayapple is toxic to dogs. Dogs are more likely than cats to eat enough to make themselves sick — the unripe green fruit and the rhizome are particularly potent, and curious dogs in wooded yards are the typical patients. Expect significant GI upset and treat ingestions as a vet call, not a wait-and-see.
What to watch for
Vomiting, diarrhea, drooling, and abdominal discomfort usually come first. Lethargy and panting are common. Skin contact with the sap can produce redness or ulcers around the muzzle. Rare severe cases progress to extreme weakness or coma — get to a vet long before then.
Time window
Specific onset timing isn't well documented, but GI signs generally appear within hours of ingestion. Most dogs recover fully within 1 to 24 hours of supportive care; large ingestions may need longer.
When to call the vet
Call your vet or Pet Poison Helpline (1-800-213-6680) for any ingestion. Bring your dog in immediately if vomiting persists more than an hour or two, if you see bloody stool, breathing changes, or unusual lethargy.
First aid at home
Remove any remaining plant material from your dog's mouth, save a leaf or piece of fruit for ID, and rinse the muzzle if sap is visible. Call your vet before giving anything by mouth. Do not induce vomiting unless directed.
Sources: ASPCA, Pet Poison Helpline.
If a pet has chewed or swallowed plant material and is showing symptoms, contact a veterinarian or poison resource immediately. This product is for structured reference, not diagnosis.
Dogs — concern notes
Common signs
Vomiting, diarrhea, excessive salivation, and signs of abdominal discomfort.
Escalation note
The plant contains compounds that can cause systemic irritation. Seek veterinary care promptly if your dog has consumed any part of this plant.
Safer alternatives
No hand-picked alternatives for this plant yet. You can still pick your own using the Compare button on any other plant.
Source evidence
Same dog verdict
Related plants for dogs
Calla Lily
Zantedeschia aethiopica
The Arum Lily is a popular ornamental plant known for its striking white spathes, but it contains insoluble calcium oxalate crystals that can cause irritation upon ingestion. It is considered toxic to both cats and dogs.
Potentially toxic for cats & dogs.
Lily of the Valley
Convallaria majalis
Lily of the Valley is a popular spring-flowering perennial known for its fragrant, bell-shaped white flowers. It contains cardiac glycosides that are highly toxic to pets if ingested.
Potentially toxic for cats & dogs.
Monstera
Monstera deliciosa
Monstera deliciosa is a popular tropical houseplant known for its large, fenestrated leaves and vining growth habit. It contains insoluble calcium oxalate crystals that can cause irritation if ingested by pets.
Potentially toxic for cats & dogs.
Snake Plant
Dracaena trifasciata
Dracaena trifasciata is a popular, hardy houseplant known for its stiff, sword-like leaves with striking yellow margins. It is widely appreciated for its air-purifying qualities and ability to thrive in various indoor conditions.
Potentially toxic for cats & dogs.