Safety verdict
Consulted references classify the plant as toxic or irritating for that pet type.
Pet ingestion lookup
My dog ate Yesterday-Today-and-Tomorrow - what should I do?
Brunfelsia species
Potentially toxic
Contact your veterinarian or an animal poison-control resource now, especially if any amount was chewed or swallowed.
Verified against ASPCA/provenance audit 2026-05-06 on May 6, 2026.
Signs to watch for
Vomiting, excessive salivation, muscle tremors, incoordination, and seizures.
Escalation note
The plant contains alkaloids that can cause severe systemic distress. Seek veterinary care promptly if your dog has consumed any part of this plant.
First aid at home
Bring any chewed plant material, seeds, or seed pods (or a clear photo) to the clinic so the team can confirm Brunfelsia. Do not induce vomiting at home, especially if your dog is tremoring or seizing — call ASPCA APCC (888-426-4435) or Pet Poison Helpline (855-764-7661) and follow their instructions while you transport.
What to watch for
Early signs are agitation, nervousness, or excitement followed by hypersalivation, vomiting, and diarrhea. Neurological signs progress to muscle tremors, shaking, muscular rigidity, paddling, incoordination, and tonic-clonic seizures that can recur for several days. Coughing and lethargy are also reported.
Time window
Clinical signs typically begin within 2 hours of exposure, sometimes longer, and can progress over hours to days. Seizures may continue for several days and require inpatient management.
When to call the vet
Call immediately. Any suspected ingestion is an emergency, and any tremor, twitching, or seizure is a reason to drive to the ER vet right now. Phone the ASPCA APCC (888-426-4435) or Pet Poison Helpline (855-764-7661) on the way.
What this means for your dog
Dogs are the species most commonly poisoned by yesterday-today-and-tomorrow — an ASPCA APCC review found 38 cases involving 42 dogs over five years, with no exposures recorded in other species. The plant's brunfelsamidine and related alkaloids cause severe, potentially fatal neurological signs, and seeds and seed pods are the most concentrated source.
Sources: ASPCA, dvm360 (Brunfelsia toxicology brief).
Source references
Poison-control resources
This page summarizes source-bound plant-safety information and is not veterinary advice.